CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Polymerase, chain B, domain 1
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q38087
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
3.1.11.-
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q38087

UniProtKB Entries (1)

Q38087
DPOL_BPR69
Enterobacteria phage RB69
DNA-directed DNA polymerase

PDB Structure

PDB 3NAE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin .
Beckman, J., Wang, M., Blaha, G., Wang, J., Konigsberg, W.H.
Biochemistry
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