CATH Classification
Level | CATH Code | Description |
---|---|---|
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3 | Alpha Beta |
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3.60 | 4-Layer Sandwich |
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3.60.21 | Purple Acid Phosphatase; chain A, domain 2 |
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3.60.21.10 | Metallo-dependent phosphatases |
Domain Context
CATH Clusters
Superfamily | 3.60.21.10 |
Functional Family | Serine/threonine-protein phosphatase |
Enzyme Information
3.1.3.16 |
Protein-serine/threonine phosphatase.
based on mapping to UniProt P62136
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).
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UniProtKB Entries (1)
P06400 |
RB_HUMAN
Homo sapiens
Retinoblastoma-associated protein
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PDB Structure
PDB | 3N5U |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein.
Nat.Struct.Mol.Biol.
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