CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family peripheral plasma membrane protein CASK isoform X2

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O14936
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O14936
CSKP_HUMAN
Homo sapiens
Peripheral plasma membrane protein CASK

PDB Structure

PDB 3MFR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Evolution of CASK into a Mg2+-sensitive kinase.
Mukherjee, K., Sharma, M., Jahn, R., Wahl, M.C., Sudhof, T.C.
Sci.Signal.
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