CATH Classification
Level | CATH Code | Description |
---|---|---|
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2 | Mainly Beta |
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2.40 | Beta Barrel |
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2.40.10 | Thrombin, subunit H |
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2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
Superfamily | Trypsin-like serine proteases |
Functional Family | Genome polyprotein |
Enzyme Information
UniProtKB Entries (2)
Q9WPH5 |
Q9WPH5_9HEPC
Hepatitis C virus subtype 1b
Genome polyprotein
|
A8DG50 |
A8DG50_9HEPC
Hepatitis C virus subtype 1a
Genome polyprotein
|
PDB Structure
PDB | 3M5M |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding.
Proc.Natl.Acad.Sci.USA
|