CATH Classification
Level | CATH Code | Description |
---|---|---|
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2 | Mainly Beta |
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2.170 | Beta Complex |
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2.170.270 | Beta-clip-like |
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2.170.270.10 | SET domain |
Domain Context
CATH Clusters
Superfamily | SET domain |
Functional Family | Histone-lysine N-methyltransferase SETD7 |
Enzyme Information
2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8WTS6
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
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UniProtKB Entries (1)
Q8WTS6 |
SETD7_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETD7
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PDB Structure
PDB | 3M59 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation.
J.Biol.Chem.
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