CATH Domain 3m59A01

Level	CATH Code	Description
	2	Mainly Beta
	2.20	Single Sheet
	2.20.110	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
	2.20.110.10	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain

Superfamily	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
Functional Family	Histone-lysine N-methyltransferase SETD7

2.1.1.43

Histone-lysine N-methyltransferase.

based on mapping to UniProt Q8WTS6

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

SETD7_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase SETD7

PDB	3M59
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation. Del Rizzo, P.A., Couture, J.F., Dirk, L.M., Strunk, B.S., Roiko, M.S., Brunzelle, J.S., Houtz, R.L., Trievel, R.C. J.Biol.Chem.