CATH Classification

Domain Context

CATH Clusters

Superfamily Acetylglutamate kinase-like
Functional Family

Enzyme Information

2.7.4.26
Isopentenyl phosphate kinase.
based on mapping to UniProt Q9HLX1
ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate.
-!- The enzyme is involved in the mevalonate pathway in Archaea. -!- The activity has also been identified in the plant Mentha piperita (peppermint). -!- It is strictly specific for ATP but can use other phosphate acceptors such as dimethylallyl phosphate, geranyl phosphate, or fosfomycin.

UniProtKB Entries (1)

Q9HLX1
IPK_THEAC
Thermoplasma acidophilum DSM 1728
Isopentenyl phosphate kinase

PDB Structure

PDB 3LKK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray structures of isopentenyl phosphate kinase.
Mabanglo, M.F., Schubert, H.L., Chen, M., Hill, C.P., Poulter, C.D.
Acs Chem.Biol.
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