CATH Domain 3letA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.3290	Fic-like fold
	1.10.3290.10	Fido-like domain

Domain Context

CATH Clusters

Superfamily	Fido-like domain
Functional Family

Enzyme Information

2.7.7.n1

Protein adenylyltransferase.

based on mapping to UniProt Q87P32

(1) ATP + [protein]-L-tyrosine = diphosphate + [protein]-O(4)- (5'-adenylyl)-L-tyrosine. (2) ATP + [protein]-L-threonine = diphosphate + [protein]-O(4)- (5'-adenylyl)-L-threonine.

UniProtKB Entries (1)

Q87P32

VOPS_VIBPA

Vibrio parahaemolyticus RIMD 2210633

Protein adenylyltransferase VopS

PDB Structure

PDB	3LET
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Kinetic Analysis of VopS with Fic Domain Supports a Direct Transfer Mechanism for AMPylation Luong, P.H., Kinch, L.N., Brautigam, C.A., Grishin, N.V., Tomchick, D.R., Orth, K. To be Published