CATH Domain 3l8nA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1000	Arf Nucleotide-binding Site Opener; domain 2
	1.10.1000.11	Arf Nucleotide-binding Site Opener,domain 2

Domain Context

CATH Clusters

Superfamily	Arf Nucleotide-binding Site Opener,domain 2
Functional Family	Brefeldin A-inhibited guanine nucleotide-exchange protein 1

Enzyme Information

UniProtKB Entries (1)

BIG2_HUMAN

Homo sapiens

Brefeldin A-inhibited guanine nucleotide-exchange protein 2

PDB Structure

PDB	3L8N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human). Northeast Structural Genomics Consortium target id HR5562A Seetharaman, J., Su, M., Forouhar, F., Wang, D., Janjua, H., Cunningham, K., Owens, L., Xiao, R., Liu, J., Baran, M.C., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L. To be Published