CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family 4-hydroxy-tetrahydrodipicolinate synthase

Enzyme Information

4.3.3.7
4-hydroxy-tetrahydrodipicolinate synthase.
based on mapping to UniProt P9WP25
Pyruvate + L-aspartate-4-semialdehyde = (4S)-4-hydroxy-2,3,4,5- tetrahydro-(2S)-dipicolinate + H(2)O.
-!- Formerly EC 4.2.1.52.

UniProtKB Entries (1)

P9WP25
DAPA_MYCTU
Mycobacterium tuberculosis H37Rv
4-hydroxy-tetrahydrodipicolinate synthase

PDB Structure

PDB 3L21
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A dimeric mutant of DHDPS from Mycobacterium tuberculosis
Evans, G.L., Schuldt, L., Griffin, M.D., Perugini, M.A., Jamerson, G.B., Devenish, S.R., Weiss, M.S., Gerrard, J.A.
To be Published
CATH-Gene3D is a Global Biodata Core Resource Learn more...