CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.10 | Arc Repressor Mutant, subunit A | |
1.10.10.2130 | DEAH helicase family, winged-helix domain |
Domain Context
CATH Clusters
Superfamily | DEAH helicase family, winged-helix domain |
Functional Family | Pre-mRNA-splicing factor ATP-dependent RNA helicase |
Enzyme Information
3.6.4.13 |
RNA helicase.
based on mapping to UniProt P53131
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
|
UniProtKB Entries (1)
P53131 |
PRP43_YEAST
Saccharomyces cerevisiae S288C
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43
|
PDB Structure
PDB | 3KX2 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural basis for the function of DEAH helicases
Embo Rep.
|