CATH Classification

Domain Context

CATH Clusters

Superfamily ATP-grasp fold, B domain
Functional Family Phosphoribosylaminoimidazole-succinocarboxamide synthase

Enzyme Information

6.3.2.6
Phosphoribosylaminoimidazolesuccinocarboxamide synthase.
based on mapping to UniProt Q2GHH2
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate.
-!- Forms part of the purine biosynthesis pathway.

UniProtKB Entries (1)

Q2GHH2
PUR7_EHRCR
Ehrlichia chaffeensis str. Arkansas
Phosphoribosylaminoimidazole-succinocarboxamide synthase

PDB Structure

PDB 3KRE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase from Ehrlichia chaffeensis at 1.8A resolution
Seattle Structural Genomics Center for Infectious Disease (SSGCID), Abendroth, J., Edwards, T.E., Staker, B.
To be Published