CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.65 | Alpha-beta prism |
|
3.65.10 | UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain |
|
3.65.10.10 | Enolpyruvate transferase domain |
Domain Context
CATH Clusters
| Superfamily | Enolpyruvate transferase domain |
| Functional Family | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
Enzyme Information
| 2.5.1.7 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
based on mapping to UniProt P0A749
Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP- N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine.
|
UniProtKB Entries (1)
| P0A749 |
MURA_ECOLI
Escherichia coli K-12
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
|
PDB Structure
| PDB | 3KQJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Natural Product Antibiotic Terreic Acid is a Mechanism-Based Inhibitor of the Bacterial Enzyme MurA in vitro but not in vivo.
To be Published
|