CATH Domain 3khgB04

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1490	Dna Ligase; domain 1
	3.30.1490.100	DNA polymerase, Y-family, little finger domain

Domain Context

CATH Clusters

Superfamily	DNA polymerase, Y-family, little finger domain
Functional Family

Enzyme Information

2.7.7.7

DNA-directed DNA polymerase.

based on mapping to UniProt Q97W02

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q97W02

DPO4_SACS2

Saccharolobus solfataricus P2

DNA polymerase IV

PDB Structure

PDB	3KHG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Rechkoblit, O., Kolbanovskiy, A., Malinina, L., Geacintov, N.E., Broyde, S., Patel, D.J. Nat.Struct.Mol.Biol.