CATH Domain 3ke1A00

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1330	60s Ribosomal Protein L30; Chain: A;
	3.30.1330.50	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

Superfamily	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Functional Family	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

4.6.1.12

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.

based on mapping to UniProt Q3JRA0

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl- D-erythritol 2,4-cyclodiphosphate + CMP.

-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

ISPF_BURP1

Burkholderia pseudomallei 1710b

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

PDB	3KE1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei. Zhang, Z., Jakkaraju, S., Blain, J., Gogol, K., Zhao, L., Hartley, R.C., Karlsson, C.A., Staker, B.L., Edwards, T.E., Stewart, L.J., Myler, P.J., Clare, M., Begley, D.W., Horn, J.R., Hagen, T.J. Bioorg.Med.Chem.Lett.