CATH Domain 3k9pB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.20	Ubiquitin-like (UB roll)
	3.10.20.90	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family	Polyubiquitin-C

Enzyme Information

UniProtKB Entries (1)

UBE2K_HUMAN

Homo sapiens

Ubiquitin-conjugating enzyme E2 K

PDB Structure

PDB	3K9P
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity Ko, S., Kang, G.B., Song, S.M., Lee, J.-G., Shin, D.Y., Yun, J.-H., Sheng, Y., Cheong, C., Jeon, Y.H., Jung, Y.-K., Arrowsmith, C.H., Avvakumov, G.V., Dhe-Paganon, S., Yoo, Y.J., Eom, S.H., Lee, W. J.Biol.Chem.