CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.1160 | Carbamate kinase | |
3.40.1160.10 | Acetylglutamate kinase-like |
Domain Context
CATH Clusters
Superfamily | Acetylglutamate kinase-like |
Functional Family |
Enzyme Information
2.7.4.26 |
Isopentenyl phosphate kinase.
based on mapping to UniProt Q60352
ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate.
-!- The enzyme is involved in the mevalonate pathway in Archaea. -!- The activity has also been identified in the plant Mentha piperita (peppermint). -!- It is strictly specific for ATP but can use other phosphate acceptors such as dimethylallyl phosphate, geranyl phosphate, or fosfomycin.
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UniProtKB Entries (1)
Q60352 |
IPK_METJA
Methanocaldococcus jannaschii DSM 2661
Isopentenyl phosphate kinase
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PDB Structure
PDB | 3K4Y |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates.
Acs Chem.Biol.
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