CATH Classification
Level | CATH Code | Description |
---|---|---|
![]() |
3 | Alpha Beta |
![]() |
3.90 | Alpha-Beta Complex |
![]() |
3.90.1240 | Zincin-like |
![]() |
3.90.1240.10 | Metalloproteases ("zincins"), catalytic domain like |
Domain Context
CATH Clusters
Superfamily | Metalloproteases ("zincins"), catalytic domain like |
Functional Family | Botulinum neurotoxin type A |
Enzyme Information
3.4.24.69 |
Bontoxilysin.
based on mapping to UniProt P0DPI1
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.
|
UniProtKB Entries (1)
P0DPI1 |
BXA1_CLOBH
Clostridium botulinum A str. Hall
Botulinum neurotoxin type A
|
PDB Structure
PDB | 3K3Q |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic alpha-Exosite Binding Region.
J.Mol.Biol.
|