CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Quinate/shikimate dehydrogenase |
Enzyme Information
| 1.1.1.- |
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt Q9X5C9
|
| 1.1.1.24 |
Quinate dehydrogenase.
based on mapping to UniProt Q9X5C9
Quinate + NAD(+) = 3-dehydroquinate + NADH.
-!- The enzyme is specific for quinate as substrate; phenylpyruvate, phenylalanine, cinnamate and shikimate will not act as substrates. -!- NAD(+) cannot be replaced by NADP(+).
|
UniProtKB Entries (1)
| Q9X5C9 |
AROE_CORGL
Corynebacterium glutamicum ATCC 13032
Quinate/shikimate dehydrogenase (NAD(+))
|
PDB Structure
| PDB | 3JYQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination.
Biol.Chem.
|