CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.2640 | Arenavirus RNA polymerase |
Domain Context
CATH Clusters
| Superfamily | Arenavirus RNA polymerase |
| Functional Family | RNA-directed RNA polymerase L |
Enzyme Information
| 2.7.7.48 |
RNA-directed RNA polymerase.
based on mapping to UniProt P14240
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.
|
| 3.1.-.- |
Acting on ester bonds.
based on mapping to UniProt P14240
|
UniProtKB Entries (1)
| P14240 |
L_LYCVA
Lymphocytic choriomeningitis virus (strain Armstrong)
RNA-directed RNA polymerase L
|
PDB Structure
| PDB | 3JSB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription
Plos Pathog.
|