CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.640 | Actin; Chain A, domain 4 |
|
3.90.640.10 | Actin; Chain A, domain 4 |
Domain Context
CATH Clusters
| Superfamily | Actin; Chain A, domain 4 |
| Functional Family | Heat shock cognate 71 kDa protein |
Enzyme Information
| 3.6.4.10 |
Non-chaperonin molecular chaperone ATPase.
based on mapping to UniProt P11021
ATP + H(2)O = ADP + phosphate.
-!- This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. -!- They comprise a number of heat-shock-cognate proteins. -!- They are also active in clathrin uncoating and in the oligomerization of actin.
|
UniProtKB Entries (1)
| P11021 |
BIP_HUMAN
Homo sapiens
Endoplasmic reticulum chaperone BiP
|
PDB Structure
| PDB | 3IUC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Plos One
|
