CATH Classification

Domain Context

CATH Clusters

Superfamily 14-3-3 domain
Functional Family 14-3-3 gamma 1

Enzyme Information

UniProtKB Entries (1)

P31947
1433S_HUMAN
Homo sapiens
14-3-3 protein sigma

PDB Structure

PDB 3IQJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Molzan, M., Schumacher, B., Ottmann, C., Baljuls, A., Polzien, L., Weyand, M., Thiel, P., Rose, R., Rose, M., Kuhenne, P., Kaiser, M., Rapp, U.R., Kuhlmann, J., Ottmann, C.
Mol.Cell.Biol.