CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10830 | F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) |
Domain Context
CATH Clusters
| Superfamily | F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) |
| Functional Family |
Enzyme Information
| 1.5.98.1 |
Methylenetetrahydromethanopterin dehydrogenase.
based on mapping to UniProt P94951
5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420 = 5,10- methenyltetrahydromethanopterin + reduced coenzyme F420.
-!- Coenzyme F420 is a 7,8-didemethyl-8-hydroxy-5-deazariboflavin derivative; methanopterin is a pterin analog. -!- The enzyme is involved in the formation of methane from CO(2) in Methanobacterium thermoautotrophicum. -!- Formerly EC 1.5.99.9.
|
UniProtKB Entries (1)
| P94951 |
MTD_METKA
Methanopyrus kandleri AV19
F420-dependent methylenetetrahydromethanopterin dehydrogenase
|
PDB Structure
| PDB | 3IQF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of the hydride transfer mechanism in F(420)-dependent methylenetetrahydromethanopterin dehydrogenase
Biochemistry
|
