CATH Domain 3ihjA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.640	Aspartate Aminotransferase; domain 2
	3.40.640.10	Type I PLP-dependent aspartate aminotransferase-like (Major domain)

Domain Context

CATH Clusters

Superfamily	Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family	Alanine aminotransferase 2

Enzyme Information

2.6.1.2

Alanine transaminase.

based on mapping to UniProt Q8TD30

L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.

-!- 2-aminobutanoate acts slowly instead of alanine.

UniProtKB Entries (1)

ALAT2_HUMAN

Homo sapiens

Alanine aminotransferase 2

PDB Structure

PDB	3IHJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Human glutamate pyruvate transaminase 2 Wisniewska, M., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Kotzsch, A., Moche, M., Nielsen, T.K., Nordlund, P., Nyman, T., Persson, C., Roos, A.K., Schutz, P., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Schuler, H. To be Published