CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.9 | D-Amino Acid Oxidase; Chain A, domain 2 | |
3.30.9.10 | D-Amino Acid Oxidase, subunit A, domain 2 |
Domain Context
CATH Clusters
Superfamily | D-Amino Acid Oxidase, subunit A, domain 2 |
Functional Family | Aklavinone 12-hydroxylase RdmE |
Enzyme Information
1.14.13.180 |
Aklavinone 12-hydroxylase.
based on mapping to UniProt Q54530
Aklavinone + NADPH + O(2) = epsilon-rhodomycinone + NADP(+) + H(2)O.
-!- The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins.
|
UniProtKB Entries (1)
Q54530 |
DNRF_STREF
Streptomyces purpurascens
Aklavinone 12-hydroxylase RdmE
|
PDB Structure
PDB | 3IHG |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural basis for substrate recognition and specificity in aklavinone-11-hydroxylase from rhodomycin biosynthesis.
J.Mol.Biol.
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