CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.210 | Uteroglobin |
|
1.10.210.20 |
Domain Context
CATH Clusters
| Superfamily | 1.10.210.20 |
| Functional Family |
Enzyme Information
| 1.13.11.47 |
3-hydroxy-4-oxoquinoline 2,4-dioxygenase.
based on mapping to UniProt O33472
3-hydroxy-1H-quinolin-4-one + O(2) = N-formylanthranilate + CO.
-!- Does not contain a metal center or organic cofactor. -!- Fission of two C-C bonds: 2,4-dioxygenolytic cleavage with concomitant release of carbon monoxide. -!- The enzyme from Pseudomonas putida is highly specific for this substrate. -!- Formerly EC 1.12.99.5 and EC 1.13.99.5.
|
UniProtKB Entries (1)
| O33472 |
QDO_PSEPU
Pseudomonas putida
1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase
|
PDB Structure
| PDB | 3IBT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for cofactor-independent dioxygenation of N-heteroaromatic compounds at the alpha/beta-hydrolase fold.
Proc.Natl.Acad.Sci.USA
|
