CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | Non-haem bromoperoxidase BPO-A2 |
Enzyme Information
| 3.1.1.2 |
Arylesterase.
based on mapping to UniProt P22862
A phenyl acetate + H(2)O = a phenol + acetate.
-!- Acts on many phenolic esters. -!- It is likely that the three forms of human paraoxonase are lactonases rather than aromatic esterases. -!- The natural substrates of the paraoxonases are lactones, with (+-)-5- hydroxy-6E,8Z,11Z,4Z-eicostetraenoic-acid 1,5-lactone being the best substrate.
|
| 1.-.-.- |
Oxidoreductases.
based on mapping to UniProt P22862
|
UniProtKB Entries (1)
| P22862 |
ESTE_PSEFL
Pseudomonas fluorescens
Arylesterase
|
PDB Structure
| PDB | 3IA2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Different active-site loop orientation in serine hydrolases versus acyltransferases.
Chembiochem
|
