CATH Domain 3i3rA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.572	Thymidylate Synthase; Chain A
	3.30.572.10	Thymidylate synthase/dCMP hydroxymethylase domain

Domain Context

CATH Clusters

Superfamily	Thymidylate synthase/dCMP hydroxymethylase domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

A7ASX7_BABBO

Babesia bovis

Bifunctional dihydrofolate reductase-thymidylate synthase

PDB Structure

PDB	3I3R
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Begley, D.W., Edwards, T.E., Raymond, A.C., Smith, E.R., Hartley, R.C., Abendroth, J., Sankaran, B., Lorimer, D.D., Myler, P.J., Staker, B.L., Stewart, L.J. Acta Crystallogr.,Sect.F