CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family | A disintegrin and metalloproteinase with thrombospondin motifs 1 |
Enzyme Information
| 3.4.24.- |
Metalloendopeptidases.
based on mapping to UniProt Q9UNA0
|
UniProtKB Entries (1)
| Q9UNA0 |
ATS5_HUMAN
Homo sapiens
A disintegrin and metalloproteinase with thrombospondin motifs 5
|
PDB Structure
| PDB | 3HY9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors
J.Biol.Chem.
|
