CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.418 | Actin-binding Protein, T-fimbrin; domain 1 |
|
1.10.418.10 | Calponin-like domain |
Domain Context
CATH Clusters
| Superfamily | Calponin-like domain |
| Functional Family | Filamin-B isoform A |
Enzyme Information
UniProtKB Entries (1)
| P21333 |
FLNA_HUMAN
Homo sapiens
Filamin-A
|
PDB Structure
| PDB | 3HOP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet.
|