CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.10 | Arc Repressor Mutant, subunit A | |
1.10.10.60 | Homeodomain-like |
Domain Context
CATH Clusters
Superfamily | Homeodomain-like |
Functional Family | DNA-directed RNA polymerases I, II, and III subunit |
Enzyme Information
2.7.7.6 |
DNA-directed RNA polymerase.
based on mapping to UniProt Q980Z8
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.
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UniProtKB Entries (2)
Q980R2 |
RPOA1_SACS2
Saccharolobus solfataricus P2
DNA-directed RNA polymerase subunit A'
|
Q9UXD9 |
Q9UXD9_SACSO
Saccharolobus solfataricus
DNA-directed RNA polymerase subunit F
|
PDB Structure
PDB | 3HKZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The X-ray crystal structure of RNA polymerase from Archaea.
Nature
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