CATH Domain 3hhuA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.565	Heat Shock Protein 90
	3.30.565.10	Histidine kinase-like ATPase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Histidine kinase-like ATPase, C-terminal domain
Functional Family	Heat shock protein HSP 90-alpha

Enzyme Information

UniProtKB Entries (1)

HS90A_HUMAN

Homo sapiens

Heat shock protein HSP 90-alpha

PDB Structure

PDB	3HHU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Potent triazolothione inhibitor of heat-shock protein-90. Feldman, R.I., Mintzer, B., Zhu, D., Wu, J.M., Biroc, S.L., Yuan, S., Emayan, K., Chang, Z., Chen, D., Arnaiz, D.O., Bryant, J., Ge, X.S., Whitlow, M., Adler, M., Polokoff, M.A., Li, W.W., Ferrer, M., Sato, T., Gu, J.M., Shen, J., Tseng, J.L., Dinter, H., Buckman, B. Chem.Biol.Drug Des.