CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.59 | Chorismate Mutase Domain, subunit A |
|
1.20.59.10 | Chorismate mutase |
Domain Context
CATH Clusters
| Superfamily | Chorismate mutase |
| Functional Family |
Enzyme Information
| 5.4.99.5 |
Chorismate mutase.
based on mapping to UniProt Q51507
Chorismate = prephenate.
|
| 4.2.99.21 |
Isochorismate lyase.
based on mapping to UniProt Q51507
Isochorismate = salicylate + pyruvate.
-!- This enzyme is part of the pathway of salicylate formation from chorismate, and forms an integral part of pathways that produce salicylate-derived siderophores, such as pyochelin and yersiniabactin.
|
UniProtKB Entries (1)
| Q51507 |
PCHB_PSEAE
Pseudomonas aeruginosa PAO1
Isochorismate pyruvate lyase
|
PDB Structure
| PDB | 3HGX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure-function analyses of isochorismate-pyruvate lyase from Pseudomonas aeruginosa suggest differing catalytic mechanisms for the two pericyclic reactions of this bifunctional enzyme.
Biochemistry
|