CATH Domain 3hamB02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.1200	Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2
	3.90.1200.10	Aminoglycoside phosphotransferase (APH), C-terminal lobe

Domain Context

CATH Clusters

Superfamily	3.90.1200.10
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q9EVD7_ENTFC

Enterococcus faecium

Aminoglycoside phosphotransferase

PDB Structure

PDB	3HAM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The crystal structures of substrate and nucleotide complexes of Enterococcus faecium aminoglycoside-2''-phosphotransferase-IIa [APH(2'')-IIa] provide insights into substrate selectivity in the APH(2'') subfamily. Young, P.G., Walanj, R., Lakshmi, V., Byrnes, L.J., Metcalf, P., Baker, E.N., Vakulenko, S.B., Smith, C.A. J.Bacteriol.