CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.10 | Jelly Rolls |
Domain Context
CATH Clusters
| Superfamily | Jelly Rolls |
| Functional Family |
Enzyme Information
| 5.3.3.19 |
3-((4R)-4-hydroxycyclohexa-1,5-dien-1-yl)-2-oxopropanoate isomerase.
based on mapping to UniProt P39639
3-((4R)-4-hydroxycyclohexa-1,5-dien-1-yl)-2-oxopropanoate = 3-((1E,4R)-4- hydroxycyclohex-2-en-1-ylidene)-2-oxopropanoate.
-!- The enzyme, characterized from the bacterium Bacillus subtilis, is involved in the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. -!- The enzyme can interconvert the (E) isomer formed in the reaction into the (Z) isomer, although this isomerization is not part of the pathway leading to bacilysin.
|
UniProtKB Entries (1)
| P39639 |
BACB_BACSU
Bacillus subtilis subsp. subtilis str. 168
H2HPP isomerase
|
PDB Structure
| PDB | 3H9A |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Analysis of multiple crystal forms of Bacillus subtilis BacB suggests a role for a metal ion as a nucleant for crystallization
Acta Crystallogr.,Sect.D
|
