CATH Classification

Domain Context

CATH Clusters

Superfamily Pancreatic trypsin inhibitor Kunitz domain
Functional Family Pancreatic trypsin inhibitor

Enzyme Information

UniProtKB Entries (2)

P00974
BPT1_BOVIN
Bos taurus
Pancreatic trypsin inhibitor
Q16651
PRSS8_HUMAN
Homo sapiens
Prostasin

PDB Structure

PDB 3GYM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations.
Spraggon, G., Hornsby, M., Shipway, A., Tully, D.C., Bursulaya, B., Danahay, H., Harris, J.L., Lesley, S.A.
Protein Sci.