CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family |
Enzyme Information
| 2.1.1.316 |
Mitomycin 6-O-methyltransferase.
based on mapping to UniProt Q9X5T6
(1) S-adenosyl-L-methionine + 6-demethylmitomycin A = S-adenosyl-L- homocysteine + mitomycin A. (2) S-adenosyl-L-methionine + 6-demethylmitomycin B = S-adenosyl-L- homocysteine + mitomycin B.
-!- The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B.
|
UniProtKB Entries (1)
| Q9X5T6 |
MMCR_STRLA
Streptomyces lavendulae
Mitomycin biosynthesis 6-O-methyltransferase
|
PDB Structure
| PDB | 3GWZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural characterization of the mitomycin 7-O-methyltransferase.
Proteins
|
