CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome P450
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q385E8
Q385E8_TRYB2
Trypanosoma brucei brucei TREU927
Lanosterol 14-alpha-demethylase

PDB Structure

PDB 3GW9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
Lepesheva, G.I., Park, H.W., Hargrove, T.Y., Vanhollebeke, B., Wawrzak, Z., Harp, J.M., Sundaramoorthy, M., Nes, W.D., Pays, E., Chaudhuri, M., Villalta, F., Waterman, M.R.
J.Biol.Chem.