CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.750 | Transcription Regulator spoIIAA |
|
3.30.750.60 | Endosialidase, N-terminal extension domain |
Domain Context
CATH Clusters
| Superfamily | Endosialidase, N-terminal extension domain |
| Functional Family |
Enzyme Information
| 3.2.1.129 |
Endo-alpha-sialidase.
based on mapping to UniProt Q04830
Endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.
-!- Although the name endo-N-acetylneuraminidase has also been used for this enzyme, this is misleading since its activity is not restricted to acetyl-substituted substrates. -!- An exo-alpha-sialidase activity is listed as EC 3.2.1.18. -!- See also 4.2.2.15.
|
UniProtKB Entries (1)
| Q04830 |
FIBER_BPK1F
Enterobacteria phage K1F
Tail spike protein
|
PDB Structure
| PDB | 3GVL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for the recognition and cleavage of polysialic acid by the bacteriophage K1F tailspike protein EndoNF.
J.Mol.Biol.
|
