CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.420.40
Functional Family Phosphotransferase

Enzyme Information

2.7.1.2
Glucokinase.
based on mapping to UniProt P35557
ATP + D-glucose = ADP + D-glucose 6-phosphate.
-!- A group of enzymes found in invertebrates and microorganisms highly specific for glucose.

UniProtKB Entries (1)

P35557
HXK4_HUMAN
Homo sapiens
Glucokinase

PDB Structure

PDB 3GOI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators
Mitsuya, M., Kamata, K., Bamba, M., Watanabe, H., Sasaki, Y., Sasaki, K., Ohyama, S., Hosaka, H., Nagata, Y., Eiki, J., Nishimura, T.
Bioorg.Med.Chem.Lett.
CATH-Gene3D is a Global Biodata Core Resource Learn more...