CATH Classification

Domain Context

CATH Clusters

Superfamily 3.70.10.10
Functional Family Cell cycle checkpoint control protein

Enzyme Information

3.1.11.2
Exodeoxyribonuclease III.
based on mapping to UniProt Q99638
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
-!- Preference for double-stranded DNA. -!- Has endonucleolytic activity near apurinic sites on DNA. -!- Similar enzyme: Haemophilus influenzae exonuclease. -!- Formerly EC 3.1.4.27.

UniProtKB Entries (1)

O60671
RAD1_HUMAN
Homo sapiens
Cell cycle checkpoint protein RAD1

PDB Structure

PDB 3GGR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex
Xu, M., Bai, L., Gong, Y., Xie, W., Hang, H.Y., Jiang, T.
J.Biol.Chem.
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