CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.80 | Peptidase S8 propeptide/proteinase inhibitor I9 |
Domain Context
CATH Clusters
| Superfamily | Peptidase S8 propeptide/proteinase inhibitor I9 |
| Functional Family | Proprotein convertase subtilisin/kexin type 9 |
Enzyme Information
| 3.4.21.- |
Serine endopeptidases.
based on mapping to UniProt Q8NBP7
|
UniProtKB Entries (1)
| Q8NBP7 |
PCSK9_HUMAN
Homo sapiens
Proprotein convertase subtilisin/kexin type 9
|
PDB Structure
| PDB | 3GCW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells.
J.Biol.Chem.
|
