CATH Classification

Domain Context

CATH Clusters

Superfamily Diaminopimelate Epimerase; Chain A, domain 1
Functional Family 3-methylitaconate isomerase

Enzyme Information

5.3.3.6
Methylitaconate Delta-isomerase.
based on mapping to UniProt Q0QLE6
Methylitaconate = 2,3-dimethylmaleate.
-!- Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri. -!- Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1, EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 4.2.1.85 and EC 4.1.3.32.

UniProtKB Entries (1)

Q0QLE6
MII_EUBBA
Eubacterium barkeri
3-methylitaconate isomerase

PDB Structure

PDB 3G7K
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure and putative mechanism of 3-methylitaconate-delta-isomerase from Eubacterium barkeri
Velarde, M., Macieira, S., Hilberg, M., Broker, G., Tu, S.-M., Golding, B.T., Pierik, A.J., Buckel, W., Messerschmidt, A.
J.Mol.Biol.
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