CATH Domain 3g5yB01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Ig heavy chain V region 36-60

Enzyme Information

UniProtKB Entries (1)

EGFR_HUMAN

Homo sapiens

Epidermal growth factor receptor

PDB Structure

PDB	3G5Y
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Antibodies specifically targeting a locally misfolded region of tumor associated EGFR Garrett, T.P.J., Burgess, A.W., Gan, H.K., Luwor, R.B., Cartwright, G., Walker, F., Orchard, S.G., Clayton, A.H.A., Nice, E.C., Rothacker, J., Catimel, B., Cavenee, W.K., Old, L.J., Stockert, E., Ritter, G., Adams, T.E., Hoyne, P.A., Wittrup, D., Chao, G., Cochran, J.R., Luo, C., Lou, M., Huyton, T., Xu, Y., Fairlie, W.D., Yao, S., Scott, A.M., Johns, T.G. Proc.Natl.Acad.Sci.USA