CATH Domain 3g0hA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	ATP-dependent RNA helicase DDX19B

Enzyme Information

3.6.4.13

RNA helicase.

based on mapping to UniProt Q9UMR2

ATP + H(2)O = ADP + phosphate.

-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q9UMR2

DD19B_HUMAN

Homo sapiens

ATP-dependent RNA helicase DDX19B

PDB Structure

PDB	3G0H
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch. Collins, R., Karlberg, T., Lehtio, L., Schutz, P., van den Berg, S., Dahlgren, L.G., Hammarstrom, M., Weigelt, J., Schuler, H. J.Biol.Chem.