CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.10 | Arc Repressor Mutant, subunit A | |
1.10.10.430 | Phosphatase 2C, C-terminal domain suprefamily |
Domain Context
CATH Clusters
Superfamily | Phosphatase 2C, C-terminal domain suprefamily |
Functional Family | Protein phosphatase, Mg2+/Mn2+ dependent 1A |
Enzyme Information
3.1.3.16 |
Protein-serine/threonine phosphatase.
based on mapping to UniProt P35813
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).
|
UniProtKB Entries (1)
P35813 |
PPM1A_HUMAN
Homo sapiens
Protein phosphatase 1A
|
PDB Structure
PDB | 3FXO |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural basis for the Mn2+-dependent activation of human PPM1A
To be published
|