CATH Classification
Domain Context
CATH Clusters
| Superfamily | Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 |
| Functional Family |
Enzyme Information
| 1.21.3.3 |
Reticuline oxidase.
based on mapping to UniProt P30986
(S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2).
-!- Acts on (S)-reticuline and related compounds, converting the N-methyl group into the methylene bridge ('berberine bridge') of (S)- tetrahydroprotoberberines. -!- The product of the reaction, (S)-scoulerine, is a precursor of protopine, protoberberine and benzophenanthridine alkaloid biosynthesis in plants. -!- Formerly EC 1.5.3.9.
|
UniProtKB Entries (1)
| P30986 |
RETO_ESCCA
Eschscholzia californica
Reticuline oxidase
|
PDB Structure
| PDB | 3FW8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural roles of biocovalent flaninylation in berberine bridge enzyme
to be published
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