CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.90 | Phospholipase A2 | |
1.20.90.10 | Phospholipase A2 domain |
Domain Context
CATH Clusters
Superfamily | Phospholipase A2 domain |
Functional Family |
Enzyme Information
3.1.1.4 |
Phospholipase A(2).
based on mapping to UniProt P00592
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.
|
UniProtKB Entries (1)
P00592 |
PA21B_PIG
Sus scrofa
Phospholipase A2, major isoenzyme
|
PDB Structure
PDB | 3FVJ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of a premicellar complex of alkyl sulfates with the interfacial binding surfaces of four subunits of phospholipase A2.
Biochim.Biophys.Acta
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