CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.2010 |
Domain Context
CATH Clusters
| Superfamily | 3.30.70.2010 |
| Functional Family | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase |
Enzyme Information
| 2.3.1.117 |
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase.
based on mapping to UniProt P9WP21
Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(2)O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.
-!- Involved in the biosynthesis of lysine in bacteria, cyanobacteria and higher plants. -!- Earlier erroneously called 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase.
|
UniProtKB Entries (1)
| P9WP21 |
DAPD_MYCTU
Mycobacterium tuberculosis H37Rv
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
|
PDB Structure
| PDB | 3FSX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The three-dimensional Structure of a mycobacterial DapD provides insights into DapD diversity and reveals unexpected particulars about the enzymatic mechanism.
J.Mol.Biol.
|