CATH Domain 3fpdA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.270	Beta-clip-like
	2.170.270.10	SET domain

Domain Context

CATH Clusters

Superfamily	SET domain
Functional Family	Euchromatic histone-lysine N-methyltransferase 2

Enzyme Information

2.1.1.-	Methyltransferases. based on mapping to UniProt Q9H9B1
2.1.1.43	Histone-lysine N-methyltransferase. based on mapping to UniProt Q9H9B1 S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

EHMT1_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase EHMT1

PDB Structure

PDB	3FPD
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294. Chang, Y., Zhang, X., Horton, J.R., Upadhyay, A.K., Spannhoff, A., Liu, J., Snyder, J.P., Bedford, M.T., Cheng, X. Nat.Struct.Mol.Biol.